Pseudomyxoma peritonei: Role of cytoreduction and intraperitoneal chemotherapy

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Pseudomyxoma peritonei: Role of cytoreduction and intraperitoneal chemotherapy

In the past, pseudomyxoma peritonei was considered as an incurable disease and often no active treatment was given. With the advent of cytoreductive surgery, including peritonectomy procedures and intraperitoneal chemotherapy, long-term survival of these patients is actually possible. A 61-year-old patient with adenocarcinoma of the appendix who presented with a clinical picture of pseudomyxoma...

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Cytoreduction and hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from pseudomyxoma peritonei.

AIM To investigate the most important aspects of hyperthermic intraperitoneal chemotherapy (HIPEC) that has been accepted as the standard treatment for pseudomyxoma peritonei (PMP), with special regard to morbidity, overall survival (OS) and disease free survival (DFS) over 10 years. METHODS Fifty-three patients affected by PMP underwent cytoreduction (CCR) and HIPEC with a "semi-closed" abdo...

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Pseudomyxoma peritonei: biological features are the dominant prognostic determinants after complete cytoreduction and hyperthermic intraperitoneal chemotherapy.

OBJECTIVE To investigate outcome and prognostic factors in patients with pesudomyxoma peritonei (PMP) treated by complete cytoreduction and hyperthermic intraperitoneal chemotherapy. BACKGROUND After comprehensive treatment, prognosis of PMP is predominantly dependent on the completeness of cytoreduction. Once complete cytoreduction is achieved, additional factors predicting long-term outcome...

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Cytoreduction including total gastrectomy for pseudomyxoma peritonei.

BACKGROUND Cytoreductive surgery supplemented by perioperative intraperitoneal chemotherapy is a therapeutic option for selected patients with pseudomyxoma peritonei syndrome. In some patients, the stomach and/or its vascular supply are so covered by mucinous tumour that total gastrectomy is required for complete resection. METHODS Forty-five patients underwent total gastrectomy with a tempor...

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Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei (Br J Surg 2001; 88: 458-63).

BACKGROUND Pseudomyxoma peritonei remains a fatal disease. However, extensive surgical cytoreduction combined with intraoperative heated intraperitoneal chemotherapy (HIPEC) has recently emerged as a new treatment modality, which might improve survival. METHODS Patients underwent treatment if the tumour appeared to be technically resectable on preoperative abdominal computed tomography and th...

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ژورنال

عنوان ژورنال: Annals of the College of Surgeons Hong Kong

سال: 2004

ISSN: 1028-4001,1442-2034

DOI: 10.1111/j.1442-2034.2003.00190.x